Profhilo®

Profhilo® is a unique injectable treatment made of pure hyaluronic acid formulated with NAHYCO® hybrid technology. Unlike dermal fillers, Profhilo doesn’t add volume — instead, it spreads evenly under the skin to stimulate natural collagen and elastin production, improving skin texture, firmness, and hydration. It acts as a powerful bioremodelling treatment, targeting skin laxity and dullness from within, making it ideal for the face, neck, and hands.

Profhilo®

Profhilo® is a unique injectable treatment made of pure hyaluronic acid formulated with NAHYCO® hybrid technology. Unlike dermal fillers, Profhilo doesn’t add volume — instead, it spreads evenly under the skin to stimulate natural collagen and elastin production, improving skin texture, firmness, and hydration. It acts as a powerful bioremodelling treatment, targeting skin laxity and dullness from within, making it ideal for the face, neck, and hands.

ABOUT PROFHILO

Profhilo is the first and most powerful bio-modelling, 1,4-butanediol diglycidyl ether (BDDE)-free, 100% pure hyaluronic acid injection that intensely hydrates, lifts, and firms to achieve skin rejuvenation from deep within. It bio-stimulates 4 types of collagen, elastin, and adipocyte (fat) stem cells to address skin laxity and hydration of the skin while enhancing fat tissue renewal to both add and restore volume to dermal tissues. Profhilo is referred to as an “injectable skincare”, it contains the highest concentration of hyaluronic acid at 64 mg/mL that will vitalise aging skin after just a few sessions without downtime.

How it Works

Hyaluronic acid is a naturally occurring chemical that our body generate. Its function is to keep the body wet and to help in the creation of collagen. It can hold 1000 times its weight in water, making it perfect for skin moisture binding. However, hyaluronic acid synthesis decreases with age, making the skin seem dull and dry, with the growth of fine lines and wrinkles.

The Bio Aesthetic Points (BAP) technique was specially developed for PROFHILO and consists of only 5 injection points on each side of the face and only 7 injection points for the neck. These points were identified using selection criteria to help minimise risks and maximise spread ability.

  • Face
    The injection point will effectively deliver the pure, premium-grade hyaluronic acid to the skin to naturally stimulate the production of collagen and elastin, resulting in significantly improved skin quality, reduced fine lines and wrinkles, and firmer skin on the face.
  • Neck
    Profhilo is effective in treating loose skin on the neck by tackling skin tissue quality. It works deep in the dermis to tighten sagging tissues in the neck area to reduce the appearance of wrinkles, making the neck appear to be more youthful.
  • 20% increase in skin hydration
  • 12x increase in collagen and elastin in the skin
  • 8x more lasting results
  • Zero to no downtime
  • Painless procedure
  • Glowing results after 2-3 sessions

PROFHILO®, being a bio-remodeling agent, takes longer to take action than other Hyaluronic Acid injectables. The outcomes are not instantaneous. Instead, your skin improves gradually over four weeks, with complete benefits visible 1-2 months after your second session.

Yes, Profhilo is known for its simplicity and comfort. It requires only five injection points per side of the face, with a very fine needle. A topical numbing cream may be used to reduce any discomfort. The treatment is quick, often completed within 15 minutes, and involves minimal pain or downtime.

Visible skin improvement can be seen as early as 1–2 weeks after the first session. For best results, a full protocol includes 2 sessions spaced one month apart, with results lasting 6 to 9 months or longer, depending on your skin condition and lifestyle. Maintenance every 6 months is often recommended for continued skin rejuvenation.

Absolutely. Profhilo® is CE-marked and widely trusted in over 70 countries, with a strong safety profile and minimal risk of adverse reactions. It contains no synthetic additives and is one of the most purified forms of hyaluronic acid available. At Zen Clinic, Profhilo is administered by licensed aesthetic doctors who follow strict medical protocols to ensure safety and natural-looking results.

No, dermal fillers work to restore/add volume in the injected area to enhance the facial structure and plump up the lines and wrinkles on the face, while Profhilo allows its formulation to flow over extended areas to boost hydration and does not work to change the structure of the face.